+ Translate
+ Most Popular
Allopurinol and Loss of Consciousness in a 78-old Year Man Suffering from Gout
The parasites of British birds and mammals. 3XIV-3XVH
Studies on the in vitro synthesis of phi x 174 super helical covalently closed circular duplex dna and circular single stranded dna
The Shahada movement: a peasant movement in Maharashtra (India) - its development and its perspectives
The cranial nerves of Wallago attu
Anatomy of Mystus seenghala IV Nervous system
Haematology of Persian fallow deer (Dama mesopotamica)
Major weeds of rabi and kharif crops and their control
Structure of Morija-Banol iron-ore deposits, Rajasthan, and its control over mineralization
Donkioporia expansa - A lesser known wood destroyer in buildings
The new physiology of vision 3Xin. The testing of color-vision
Economic importance of Pteridophytes
Comparison of rice bran and maize bran as feeds for growing and fattening pigs
Ketoconazole shampoo 1% vs. climbazole shampoo in the treatment of seborrhoeic scalp dermatitis
Economic efficiency of biwall drip irrigation in sugarcane production - a case study in Ankalkhop village in Sangli District of Maharashtra
48,4X-49,5X mosaic: asynchronies among the late-replicating X chromosomes
Compatibility of potassium phosphonate (Akomin-40) with different species of Trichoderma and Gliocladium virens
Enterobacter amnigenus. An unusual human pathogen
The 48 4X 49 4Xy 49 4X iso chromosome yq mosaicism in a 3 year old boy from a twin pregnancy
Placentrex treatment in corneal defects in animals
The biology of human starvation: some new insights
Real-time PCR assays for the specific detection of monkeypox virus West African and Congo Basin strain DNA
Replenishable but depletable resources: water
New insights into bestiality and zoophilia
Thoracic outlet syndrome in Ehlers-Danlos patients as displayed by magnetic resonance imaging, angiography and venography

Spontaneous human herpes virus type 1 infection in a chinchilla (Chinchilla lanigera f. dom.)

Spontaneous human herpes virus type 1 infection in a chinchilla (Chinchilla lanigera f. dom.)

Acta Neuropathologica 104(6): 674-678

ISSN/ISBN: 0001-6322

PMID: 12410390

DOI: 10.1007/s00401-002-0597-6

A 1-year-old male chinchilla with a 2-week history of conjunctivitis suffered subsequently from neurological signs comprising seizures, disorientation, recumbency and apathy. After 3 weeks of progressive central nervous disease the animal was killed in view of the poor prognosis. A non-suppurative meningitis and polioencephalitis with neuronal necrosis and intranuclear inclusion bodies were observed at necropsy and by light microscopy. The brain stem and cerebral cortices were most severely affected. Both eyes displayed ulcerative keratitis, uveitis, retinitis and retinal degeneration, and optical neuritis. Additionally, a purulent rhinitis with focal erosions, epithelial degeneration and intranuclear inclusion bodies was present. Ultrastructurally, herpes virus particles were detected in neurons of the brain. Immunohistochemistry with antisera specific for human herpes virus types 1 and 2 resulted in viral antigen labeling in neurons, glial cells and in neuronal processes. Viral antigen was found in the rhinencephalon, cerebral cortices, hippocampus, numerous nuclei of the brain stem, single foci in the cerebellum, and in a solitary erosive lesion of the right nasal vestibulum. Viral antigen was not detected in the eyes. The virus was isolated from the CNS, and nucleic acid sequence analysis of the glycoprotein B and the DNA polymerase revealed a sequence homology with human herpes virus type 1 of 99% and 100%, respectively. The clinical signs, the distribution of the lesions and the viral antigen suggest a primary ocular infection with subsequent spread to the CNS. Chinchillas are susceptible to human herpes virus 1 and may play a role as a temporary reservoir for human infections.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 011390240

Download citation: RISBibTeXText

Related references

Megaesophagus in a chinchilla Chinchilla lanigera A case report Megaoesophagus bei einem Chinchilla Chinchilla lanigera Ein Fallbericht. Tieraerztliche Praxis Ausgabe K Kleintiere Heimtiere 322: 96-100, 2004

Spontaneous Proteus mirabilis and Enterobacter aerogenes infection in chinchilla (Chinchilla lanigera). Scientifur 31(1/2): 27-30, 2007

Preservation of chinchilla genital system Chinchilla lanigera for microscopic evaluation Preservacao do sistema genital de chinchila Chinchilla lanigera para avaliacao em microscopia de luz. Arquivo Brasileiro de Medicina Veterinaria e Zootecnia 58(6): 1247-1248, 2006

Spontaneous sister chromatid exchange in mitotic chromosomes of the chinchilla (Chinchilla lanigera). Canadian Journal of Animal Science 95(4): 543-550, 2015

Spontaneous herpes-like viral infection in a chinchilla (Chinchilla laniger). Journal of Wildlife Diseases 6(3): 175-179, 1970

Streptococcus equi subspecies zooepidemicus infection in a pet chinchilla (Chinchilla lanigera). Journal of Exotic Pet Medicine 31: 36-38, 2019

Cost-benefit relationship in thermoregulation of Chinchilla lanigera Relacion costo-beneficio en la termorregulacion de Chinchilla lanigera. Revista Chilena de Historia Natural. Junio; 732: 351-357, 2000

Concurrent infection with Mycobacterium avium subsp. hominissuis and Giardia duodenalis in a chinchilla (Chinchilla lanigera f. dom.). Berliner und Munchener Tierarztliche Wochenschrift 129(5-6): 242-246, 2016

Disseminated Mycobacterium genavense infection in a chinchilla (Chinchilla lanigera). Journal of Comparative Pathology 151(1): 122-125, 2014

Collaterals branches of the aortic arch and its main rami in chinchila Chinchilla lanigera Ramos colaterais do arco aortico e suas principais ramificacoes em chinchila Chinchilla lanigera. Revista Portuguesa de Ciencias Veterinarias. Jan-Mar; 99549: 53-58, 2004

Cellular blood constituents and serum protein fractions of the chinchilla (Chinchilla lanigera). Canadian Journal of Zoology 49(8): 1079-1084, 1971

Sodium carbonate intoxication on a chinchilla (Chinchilla lanigera) farm: a case report. Veterinarni Medicina 59(2): 112-116, 2014

Effect of different light intensity during chinchilla (Chinchilla lanigera) raising on the quality of their pelts. Folia Universitatis Agriculturae Stetinensis, Zootechnica (48): 157-167, 2006

Generalized Edema and Chylothorax in a 5-Year-Old Female Intact CHINCHILLA (CHINCHILLA LANIGERA). Journal of Exotic Pet Medicine 26(3): 219-223, 2017

Sound pressure transformations by the head and pinnae of the adult Chinchilla (Chinchilla lanigera). Hearing Research 272(1-2): 135-147, 2011