Section 12
Chapter 11,403

Streptococcus intermedius, Streptococcus constellatus, and Streptococcus anginosus ("Streptococcus milleri group") are of different clinical importance and are not equally associated with abscess

Claridge, J.E.; Attorri, S.; Musher, D.M.; Hebert, J.; Dunbar, S.

Clinical Infectious Diseases An Official Publication of the Infectious Diseases Society of America 32(10): 1511-1515


ISSN/ISBN: 1058-4838
PMID: 11317256
DOI: 10.1086/320163
Accession: 011402652

Difficulties in distinguishing organisms of the "Streptococcus milleri group" (SMG; Streptococcus intermedius, Streptococcus constellatus, and Streptococcus anginosus), have caused ambiguity in determining their pathogenic potential. We reviewed 118 cases in which SMG isolates had been identified using 16S rDNA sequence. S. constellatus and S. anginosus were isolated far more frequently than was S. intermedius. Nearly all isolates of S. intermedius and most isolates of S. constellatus, but only 19% of those of S. anginosus, were associated with abscess. Our findings suggest that speciation of the SMG may guide diagnostic evaluation, give insight into the possible role of coinfecting organisms, and help assess the need to search for occult abscess.

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