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Survival and prognostic factors in resected N0 non-small cell lung cancer



Survival and prognostic factors in resected N0 non-small cell lung cancer



Zhongguo Zhongliu Linchuang 30(3): 187-189



Objective: The prognostic factors for N0 non-small cell lung cancer undergone radical resection were retrospectively reviewed. Methods: The present study comprised 248 consecutive patients from Tianjin Cancer Hospital and Institute (1994.1-1997.7) who underwent surgical resection of N0 NSCLC. Kaplan-meier survival curve and Cox regression model were used to evaluate the prognostic faceors. Results: The patients who were resected more than 6 lymph nodes in the ipsilateral hilum and mediastina during the operation had a higher survival rate than the others (P = 0.005). The survival rates were gradually decreased from T1, T2, T3 and T4 (P < 0.001). Patients had not received postoperative chemotherapy gave a poorer survival than who had (P = 0.016). Patients with squamous carcinoma and adenocarcinoma gave a better survival rate than the other kinds (P = 0.002). Conclusion: The number of lymph nodes resected, T stage, postoperative chemotherapy and pathologic type are the main prognostic factors. The other factors had no significant effect of the prognosis.

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