+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Testicular-sparing surgery for the prepubertal testicular tumor. Experience of two cases with large cell calcifying Sertoli cell tumors



Testicular-sparing surgery for the prepubertal testicular tumor. Experience of two cases with large cell calcifying Sertoli cell tumors



European Urology 40(6): 699-704



Purpose: We review prepubertal germ cell tumors of testis in our institute and the Japanese registry and present 2 cases with a large cell calcifying Sertoli cell tumor (LCCSCT) and discuss the possibility of testis-sparing surgery. Materials and Methods: Incidence, age, pathology and clinical stages of prepubertal germ cell tumors are surveyed for 30 years at our department and 10 years of the malignant tumor registry of the Japanese Society of Pediatric Surgery. Two representative prepubertal boys with LCCSCT are presented. One of them was treated by partial orchiectomy. Results: The majority of testicular germ cell tumors in the prepubertal age were composed of embryonal cell carcinoma/yolk sac tumors or teratoma, occurred in preschool age, were limited to clinical stage I and did not metastasize irrespective of histology. Benign behavior which included recovery from hormonal derangement, no tumor recurrence and negative antisperm antigen was observed in 2 cases with LCCSCT who underwent either radical orchiectomy or partial orchiectomy. Conclusion: Partial orchiectomy should be considered as a standard option in prepubertal schoolboys with a testicular mass if surgically feasible. This surgical treatment is safe and preserves fertility and is psychologically advantageous. It is not recommended for yolk sac tumors that may recur, however they are rare in prepubertal boys and can be differentiated preoperatively by prudent evaluation.

(PDF emailed within 1 workday: $29.90)

Accession: 011461309

Download citation: RISBibTeXText

PMID: 11805420


Related references

Testis-sparing surgery of unilateral testicular large-cell calcifying Sertoli cell tumor: a sporadic case. Turkish Journal of Urology 44(4): 370-372, 2018

Organ-sparing surgery of the bilateral testicular large cell calcifying sertoli cell tumor in patient with atypical Peutz-Jeghers syndrome. International Urology and Nephrology 44(4): 1045-1048, 2012

Testicular steroid biosynthesis in a boy with a large cell calcifying Sertoli cell tumor producing prepubertal gynecomastia. Steroids 60(2): 220-225, 1995

Bilateral testicular large-cell calcifying sertoli cell tumor and recurrent cardiac myxoma in a patient with Carney's complex. Pediatric Radiology 25 Suppl 1: S236-S237, 1995

A Hard Ball for a Tennis Player: A Rare Case of Large Calcifying Sertoli Cell Testicular Tumor. Urology Case Reports 13: 55-57, 2017

Prepubertal testicular tumours: Should testicular-sparing surgery be considered? A single-institution experience and review of the literature. Arab Journal of Urology 12(2): 130-136, 2015

Testicular–Sparing Surgery for the Prepubertal Testicular Tumor. European Urology 40(6): 699-704, 2001

Prepubertal Malignant Large Cell Calcifying Sertoli Cell Tumor of the Testis. Urology 117: 145-149, 2018

Testicular juvenile granulosa cell and Sertoli cell tumors: A clinicopathological study of 29 cases from the Kiel Paediatric tumor registry. Virchows Archiv 430(4): 301-309, 1997

Organ-sparing surgery for large cell calcifying Sertoli cell tumour in a patient with Carney complex. BMJ Case Reports 2017, 2018

Sertoli cell tumor in a prepubertal boy mimicking testicular torsion. Urologia Internationalis 65(4): 211-213, 2000

Testis sparing surgery in the treatment of bilateral testicular germ cell tumors and solitary testicle tumors: A single institution experience. Journal of Surgical Oncology 111(2): 226-230, 2015

Testicular neoplasms (germ cell tumors, Leydig cell tumor, Sertoli cell tumor). Nihon Rinsho. Japanese Journal of Clinical Medicine Suppl 2: 291-295, 2006

Tumor markers in testicular germ cell tumors 5 year experience from the danish testicular carcinoma study 1976 1980. Acta Radiologica Oncology 23(4): 287-294, 1984

Large cell calcifying Sertoli cell tumor of the testis: contrasting features of six malignant and six benign tumors and a review of the literature. American Journal of Surgical Pathology 21(11): 1271-1280, 1997