+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Trends in epidemiology of preinvasive and invasive vulvar neoplasias. 13 year retrospective analysis in Thrace, Greece

Trends in epidemiology of preinvasive and invasive vulvar neoplasias. 13 year retrospective analysis in Thrace, Greece

Archives of Gynecology and Obstetrics 264(2): 74-79

Objective: To describe the trends in incidence of preinvasive and invasive vulvar neoplasias in the rural area of Trace, as well as to check the hypothesis that patients found with these two distinct entities represent populations with different epidemiologic characteristics. Patients and Methods: We performed a retrospective study on 34 patients found with invasive vulvar cancer and vulvar intraepithelial neoplasia (VIN) (12 and 22 respectively), who referred to our department from 1986-1998. Epidemiologic characteristics of the patients were abstracted from medical charts. To evaluate our results we used the direct standardization method (1995 Eur. Population) and chi2 test. Results: The age-adjusted incidence rates for VIN1-2, in situ cancer (CIS)-VIN3 and invasive vulvar cancer were 0.9100,000, 1.6100,000 and 1.8100,000 respectively, while for the whole VIN lesions 2.5100,000. There were statistically significant differences in most epidemiologic characteristics between the two study groups, one with invasive cancer patients and one with patients found with preinvasive vulvar neoplasia. Conclusions: The overall age-adjusted incidence rate for vulvar neoplasia in Thrace is comparable to the one reported in literature. Our study results confirm that patients with invasive and preinvasive vulvar neoplasia represent populations with different epidemiologic characteristics.

(PDF emailed within 1 workday: $29.90)

Accession: 011594477

Download citation: RISBibTeXText

PMID: 11045327

Related references

Trends in epidemiology of cervical cancer in Thrace, Greece. International Journal of Gynaecology and Obstetrics: the Official Organ of the International Federation of Gynaecology and Obstetrics 68(1): 59-60, 2000

Diagnosis and management of vulvar intraepithelial neoplasias and invasive vulvar cancers. Gynakologisch-Geburtshilfliche Rundschau 47(2): 88-93, 2007

Biomarkers--the new frontier in the pathology of invasive and preinvasive neoplasias. Biotechnic & Histochemistry 72(2): 59-61, 1997

Epidemiology and survival of patients with well-differentiated thyroid cancer subjected to total thyroidectomy in Thrace area, Northern Greece: a 20-year experience. Minerva Chirurgica 65(2): 137-143, 2011

Sequence Variation of Human Papillomavirus Type 16 E7 in Preinvasive and Invasive Cervical Neoplasias. Virus Genes 9(1): 85-92, 1994

Trends in the epidemiology of hepatitis B virus infection at a tertiary care hospital: A 10-year retrospective analysis. Indian Journal of Gastroenterology 34(2): 189-190, 2016

Epidemiology of vulvar intra-epithelial neoplasias. Gynecologie, Obstetrique & Fertilite 35(12): 1251-1256, 2007

Clinical aspects and morphology of preinvasive and invasive forms of vulvar neoplasms. Zeitschrift für Arztliche Fortbildung 71(12): 573-577, 1977

Is it rational to start population-based cervical cancer screening at or soon after age 20? Analysis of time trends in preinvasive and invasive diseases. European Journal of Cancer 43(4): 769-774, 2007

Ovarian cancer epidemiology in Thrace, Greece. European Journal of Gynaecological Oncology 21(3): 298-302, 2000

Proliferating cell nuclear antigen pcna in vulvar intraepithelial neoplasias vin and invasive carcinomas. Laboratory Investigation 66(1): 66A, 1992

Human papillomavirus type 16 and risk of preinvasive and invasive vulvar cancer: results from a seroepidemiological case-control study. Obstetrics and Gynecology 91(4): 638-638, 1998

Trends in breast cancer incidence in Thrace, Greece: an epidemiological assessment. European Journal of Gynaecological Oncology 21(1): 76-80, 2000

Preinvasive vulvar and cervical cancer in a 32-year-old woman, DNA HPV 16 positive with mtDNA mutation--case study. Ginekologia Polska 80(7): 533-537, 2009