+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

What determines the size of teleost erythrocytes? Correlations with oxygen transport and nuclear volume



What determines the size of teleost erythrocytes? Correlations with oxygen transport and nuclear volume



Fish Physiology & Biochemistry 20(1): 31-35



An inverse relationship exists between erythrocyte size and the aerobic swimming ability of teleosts. A functional basis for this relationship is found in larger surface area to volume ratios and shorter diffusion distances allowing more rapid oxygen transfer as erythrocyte volume decreases. However, this apparently simple functional relationship is confounded by a more general direct relationship between cell size and nuclear volume. Nuclear DNA content, which is directly proportional to nuclear volume, is known to vary at least 11 fold among teleost species. Therefore a question arises as to the relative contributions of nuclear volume and the demands of the blood oxygen delivery system in determining erythrocyte volume. These relationships were investigated by regressing erythrocyte volume against nuclear volume and whole blood haemoglobin concentration (as an index of aerobic scope) for 52 species of teleost fish from 25 families. This analysis shows that erythrocyte volume is more highly correlated with oxygen delivery than with nuclear volume. However, much of the variation in erythrocyte volume is unexplained.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 011650735

Download citation: RISBibTeXText

DOI: 10.1023/a:1007785202280


Related references

Volume changes of erythrocytes after x-ray irradiation,. Use of automatic methods of determination of the middle volume and size distribution of blood cells with membrane examination of irradiated erythrocytes. Strahlentherapie 139(4): 465-471, 1970

Volume-weighted mean nuclear volume and nuclear area in advanced ovarian carcinoma. An investigation of sampling methods, sample size and reproducibility. Analytical and Quantitative Cytology and Histology 17(4): 284-290, 1995

Distal and proximal ligand interactions in heme proteins: correlations between C-O and Fe-C vibrational frequencies, oxygen-17 and carbon-13 nuclear magnetic resonance chemical shifts, and oxygen-17 nuclear quadrupole coupling constants in C17O- and 13CO-labeled species. Biochemistry 30(9): 2333-2347, 1991

Correlations between nuclear volume, cell volume and DNA content in meristematic cells of herbaceous angiosperms. Experientia 29(8): 1028-1029, 1973

Oxygen and carbon dioxide transport in vertebrate erythrocytes: an evolutionary change in the role of membrane transport. Journal of Experimental Biology 200(Pt 2): 369-380, 1997

Correlations between parameters characterizing the volume and number of erythrocytes and platelets in human blood. Fiziologiia Cheloveka 30(3): 136-139, 2004

Hyperbaric oxygen therapy: size of infarct determines therapeutic efficacy. Annals of Internal Medicine 78(1): 77-80, 1973

Evidence for chloride dependent potassium and water transport induced by hypo osmotic stress in erythrocytes of the marine teleost opsanus tau. Journal of Comparative Physiology B Biochemical Systemic & Environmental Physiology 146(1): 9-16, 1982

Distal and proximal ligand interactions in heme proteins correlations between carbon oxygen and iron carbon vibrational frequencies oxygen 17 and carbon 13 nmr chemical shifts and oxygen 17 nuclear quadrupole coupling constants in carbon oxygen 17 labeled and carbon 13 monoxide labeled species. Biochemistry 30(9): 2333-2347, 1991

Cardiac stroke volume and oxygen transport during volume controlled self-ventilation. Medizinische Klinik 90(1 Suppl 1): 7-8, 1995

Environmental perturbations of oxygen transport in teleost fishes: causes, consequences and compensations. Fish and Fisheries Series 9: 161-179, 1993

On the mutual relation between pH and the osmotic pressure with regard to the change in the volume of erythrocytes. I. Experiments with erythrocytes of normal animals of various kinds. II. 1. Erythrocytes in the case of jaundice. 2. Erythrocytes in renal disturbance. 3. Investigation with erythrocytes of patients suffering from various kinds of diseases. Jour Gastroenterol [in Japanese] 4(2-3-4-5): 212-398, 473-528, 589-612, 760-808, 1929

Transepithelial transport and cell volume control in proximal renal tubules from the teleost Carassius auratus. Acta Physiologica Scandinavica 160(3): 267-276, 1997