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Alpha-Naphthylisothiocyanate (ANIT) induced cholestasis in rats

Alpha-Naphthylisothiocyanate (ANIT) induced cholestasis in rats

Yonago Acta Medica 45(2): 59-68

In order to distinguish the disorder of bile acid and cholesterol metabolism in alpha-naphthylisothiocyanate (ANIT)-induced cholestasis, we examined changes in bile acid levels and compositions in bile, serum, feces and urine, as well as cholesterol levels in bile, serum, liver and feces in Wistar male rats (10-13 weeks) after a single oral administration of 100 mg/kg of ANIT.

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Accession: 011661931

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