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A novel method to prepare highly encapsulated interferon-alpha-2b containing liposomes for intramuscular sustained release



A novel method to prepare highly encapsulated interferon-alpha-2b containing liposomes for intramuscular sustained release



European Journal of Pharmaceutics and Biopharmaceutics 64(1): 9-15



A novel modified film-hydration-dilution method was employed to prepare highly encapsulated interferon-alpha-2b containing liposomes for intramuscular sustained release. The liposomes produced by this technique were a mixture of mainly unilamellar vesicles and a small number of multilamellar vesicles. The trapping efficiency was above 80%.

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Accession: 011698756

Download citation: RISBibTeXText

PMID: 16797953

DOI: 10.1016/j.ejpb.2006.03.003


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