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A polymorphism at codon 133 of the tumor suppressor RASSF1A is associated with tumorous alteration of the breast



A polymorphism at codon 133 of the tumor suppressor RASSF1A is associated with tumorous alteration of the breast



International Journal of Oncology 27(1): 185-191



The tumor suppressor gene RASSF1A is inactivated or mutated in different tumor entities including breast cancer. The frequency of the genomic variants of RASSF1A in patients with breast tumors has not been evaluated. We studied the association between ten nucleotide polymorphisms of RASSF1A and the risk of breast cancer in 178 cases with tumorous alterations of mammary tissue (including 141 carcinomas and 37 fibroadenomas) and 70 controls by SSCP and sequencing.

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Accession: 011701748

Download citation: RISBibTeXText

PMID: 15942659

DOI: 10.3892/ijo.27.1.185



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