+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Antibiotic-induced release of inflammatory mediators from bacteria in experimental Klebsiella pneumoniae-induced sepsis

Antibiotic-induced release of inflammatory mediators from bacteria in experimental Klebsiella pneumoniae-induced sepsis

Folia Microbiologica 50(2): 167-171

In a fibrin-clot model of sepsis, developed in mice, treatment with the antibiotics ceftazidime (Cfz) and ofloxacin (Ofl) caused significant (p < 0.01) release of endotoxin and TNF-alpha after 4.5 h when compared with control (untreated) and amikacin (Ami) treated group. Except for control group, the level of bacteremia declined in all three antibiotic-treated groups.

(PDF emailed within 1 workday: $29.90)

Accession: 011766266

Download citation: RISBibTeXText

PMID: 16110923

Related references

Antibiotic-induced release of inflammatory mediators from bacteria in experimentalKlebsiella pneumoniae-induced sepsis. Folia Microbiologica 50(2): 167-171, 2005

Intravenous 2-chloroadenosine protects BALB/c mice from Klebsiella pneumoniae B5055-induced sepsis by modulating the pro-inflammatory immune response. Journal of ChemoTherapy 21(6): 639-645, 2010

Efficacy of tigecycline, polymyxin, gentamicin, meropenem and associations in experimental Klebsiella pneumoniae carbapenemase-producing Klebsiella pneumoniae non-lethal sepsis. Brazilian Journal of Infectious Diseases 18(5): 574-575, 2015

Combination of antibiotic treatment with the thrombin inhibitor recombinant hirudin for the therapy of experimental Klebsiella pneumoniae sepsis. Thrombosis and Haemostasis 71(6): 768-772, 1994

Antibiotic-induced endotoxin release is organism-dependent in experimental sepsis. Abstracts of the Interscience Conference on Antimicrobial Agents & Chemotherapy 36(0): 144, 1996

The in vivo significance of antibiotic-induced endotoxin release in experimental Gram-negative sepsis. Journal of Endotoxin Research 3(3): 245-252, 1996

Antibiotic-induced endotoxin release is organism-dependent in experimental gram-negative sepsis. Journal of Endotoxin Research 4(5): 315-323, 1997

The significance of endotoxin release in experimental and clinical sepsis in surgical patients. Evidence for antibiotic-induced endotoxin release?. Infection 26(2): 77-84, March-April, 1998

Reduction of mortality with antithrombin III in septicemic rats: a study of Klebsiella pneumoniae induced sepsis. Thrombosis and Haemostasis 69(2): 98-102, 1993

A combination of thalidomide and augmentin protects BALB/c mice suffering from Klebsiella pneumoniae B5055-induced sepsis. Journal of ChemoTherapy 21(2): 159-164, 2009

Acute lung inflammation in Klebsiella pneumoniae B5055-induced pneumonia and sepsis in BALB/c mice: a comparative study. Inflammation 34(5): 452-462, 2012

Protective activity of klebsiella cell free vaccine with respect to sepsis induced by some streptococcus pneumoniae serotypes in mice. Zhurnal Mikrobiologii Epidemiologii i Immunobiologii (2): 60-65, 1985

Differential host inflammatory responses to viable versus antibiotic-killed bacteria in experimental microbial sepsis. Infection and Immunity 68(4): 2301-2308, 2000

Clinical characteristics of neonatal Klebsiella pneumoniae sepsis and the antibiotic sensitivity pattern of strains. Zhongguo Dang Dai Er Ke Za Zhi 12(9): 700-703, 2010

Role of Peptidylarginine Deiminase 4 in Neutrophil Extracellular Trap Formation and Host Defense during Klebsiella pneumoniae-Induced Pneumonia-Derived Sepsis. Journal of Immunology, 2018