+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Association between reduced extraversion and right posterior fusiform gyrus gray matter reduction in chronic schizophrenia



Association between reduced extraversion and right posterior fusiform gyrus gray matter reduction in chronic schizophrenia



American Journal of Psychiatry 162(3): 599-601



Objective: The authors examined the association between volume of the fusiform gyrus, a region involved in face processing, and the personality trait of extraversion in patients with schizophrenia.Method: Male patients (N = 24) and age-matched male comparison subjects (N = 26) completed NEO Five-Factor Inventory personality measures of extraversion and underwent high-spatial-resolution magnetic resonance imaging of anterior and posterior fusiform gyrus gray matter.Results: Low extraversion scores were significantly correlated with gray matter volume reductions in the right posterior fusiform gyrus for patients but not comparison subjects.Conclusions: Reduced right posterior fusiform gyrus volume may contribute to disease-related social disturbances, characterized by both low extraversion and reduced sensitivity to human faces.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 011785632

Download citation: RISBibTeXText

PMID: 15741479

DOI: 10.1176/appi.ajp.162.3.599


Related references

Fusiform gyrus gray matter reduction and visual processing in schizophrenia. Society for Neuroscience Abstract Viewer & Itinerary Planner : Abstract No 314 18, 2003

Temporal lobe gray matter in schizophrenia spectrum: a volumetric MRI study of the fusiform gyrus, parahippocampal gyrus, and middle and inferior temporal gyri. Schizophrenia Research 87(1-3): 116-126, 2006

Anomalous asymmetry of fusiform and parahippocampal gyrus gray matter in schizophrenia: A postmortem study. American Journal of Psychiatry 157(1): 40-47, 2000

Gray matter volume reduction in rostral middle frontal gyrus in patients with chronic schizophrenia. Schizophrenia Research 123(2-3): 153-159, 2010

Fusiform gyrus volume reduction and facial recognition in chronic schizophrenia. Archives of General Psychiatry 60(4): 349-355, 2003

Reduced gray matter in the anterior cingulate gyrus in familial schizophrenia: a preliminary report. Schizophrenia Research 122(1-3): 81-84, 2010

Association of schizophrenia in 22q11.2 deletion syndrome and gray matter volumetric deficits in the superior temporal gyrus. American Journal of Psychiatry 168(5): 522-529, 2011

Middle and inferior temporal gyrus gray matter volume abnormalities in chronic schizophrenia: an MRI study. American Journal of Psychiatry 161(9): 1603-1611, 2004

A prospective longitudinal volumetric MRI study of superior temporal gyrus gray matter and amygdala-hippocampal complex in chronic schizophrenia. Schizophrenia Research 113(1): 84-94, 2009

Reduced fronto-temporal connectivity is associated with frontal gray matter density reduction and neuropsychological deficit in schizophrenia. Schizophrenia Research 108(1-3): 57-68, 2009

Fusiform gyrus volume reduction in first-episode schizophrenia: a magnetic resonance imaging study. Archives of General Psychiatry 59(9): 775-781, 2002

Reduced GABAA receptors and benzodiazepine binding sites in the posterior cingulate cortex and fusiform gyrus in autism. Brain Research 1380: 218-228, 2011

Lack of progressive gray matter reduction of the superior temporal subregions in chronic schizophrenia. Schizophrenia Research 117(1): 101-102, 2010

Association of DISC1/TRAX haplotypes with schizophrenia, reduced prefrontal gray matter, and impaired short- and long-term memory. Archives of General Psychiatry 62(11): 1205-1213, 2005

Decreased gray matter volume in the left middle temporal gyrus as a candidate biomarker for schizophrenia: a study of drug naive, first-episode schizophrenia patients and unaffected siblings. Schizophrenia Research 159(1): 43-50, 2014