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Association of beta-adrenergic receptor polymorphisms and progression to heart failure in patients with idiopathic dilated cardiomyopathy



Association of beta-adrenergic receptor polymorphisms and progression to heart failure in patients with idiopathic dilated cardiomyopathy



American Journal of Medicine 117(7): 451-458



PURPOSE. Increased sympathetic nervous system activation via the P-adrenergic pathway influences the evolution of idiopathic dilated cardiomyopathy. We assessed the effects of beta-adrenergic receptor variants on heart failure in idiopathic dilated cardiomyopathy. METHODS. We prospectively analyzed 171 consecutive patients (mean (+/- SDI age, 49 +/- 14 years; 129 men) with idiopathic dilated cardiomyopathy who were receiving conventional treatment.

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Accession: 011786439

Download citation: RISBibTeXText

PMID: 15464701

DOI: 10.1016/j.amjmed.2004.04.012


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