+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Bacterial quorum-sensing signals are inactivated by mammalian cells



Bacterial quorum-sensing signals are inactivated by mammalian cells



Proceedings of the National Academy of Sciences of the United States of America 101(12): 3993-3994



Small interfering RNAs (siRNAs) potently silence expression of target genes. In principle siRNA libraries can be used to perform effective genome-scale functional genetic screens in mammalian cells, but their development has been hampered by the need to chemically synthesize thousands of oligonucleotides and to incorporate them into expression vectors.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 011797470

Download citation: RISBibTeXText

PMID: 15024108

DOI: 10.1073/pnas.0400874101


Related references

Perception and degradation of N-acyl homoserine lactone quorum sensing signals by mammalian and plant cells. Chemical Reviews 111(1): 100-116, 2011

Quorum sensing signals are produced by Aeromonas salmonicida and quorum sensing inhibitors can reduce production of a potential virulence factor. Diseases of Aquatic Organisms 78(2): 105-113, 2007

Is there a role for quorum sensing signals in bacterial biofilms?. Current Opinion in Microbiology 5(3): 254-258, 2002

Plant responses to bacterial quorum sensing signals. Current Opinion in Plant Biology 7(4): 429-433, 2004

Detection of bacterial homoserine lactone quorum sensing signals. Molecular microbial ecology manual Volumes 1 and 2 (Ed.2): 1629-1649, 2004

Bacterial quorum sensing: signals, circuits, and implications for biofilms and disease. Annual Review of Biomedical Engineering 10: 145-167, 2008

Involvement of bacterial quorum-sensing signals in spoilage of bean sprouts. Applied and Environmental Microbiology 71(6): 3321-3330, 2005

Extensive and specific responses of a eukaryote to bacterial quorum-sensing signals. Proceedings of the National Academy of Sciences of the United States of America 100(3): 1444-1449, 2003

Multiple bacterial quorum-sensing signals produced by transgenic plants. Plant Biology (Rockville) : 169, 2001

Bacterial interspecies quorum sensing in the mammalian gut microbiota. Comptes Rendus Biologies 341(5): 297-299, 2018

Gene expression in Salmonella enterica serotype typhimurium luxS mutant in response to quorum sensing signals and a poultry meat-derived quorum sensing inhibitor using microarray-based studies. Abstracts of the General Meeting of the American Society for 106): 449-450, 2006

Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms. Nature London 407(6805): 762-764, 2000

Quorum-sensing signals and quorum-sensing genes in Burkholderia vietnamiensis. Journal of Bacteriology 184(4): 87-91, 2002

Indole inhibits bacterial quorum sensing signal transmission by interfering with quorum sensing regulator folding. Microbiology 159(Pt 12): 2616-2625, 2013

Bacterial response to siderophore and quorum-sensing chemical signals in the seawater microbial community. BMC Microbiology 1(27 Cited May 17, 2002): 1-11, 2001