EurekaMag.com logo
+ Site Statistics
References:
53,869,633
Abstracts:
29,686,251
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Bilateral central giant cell granulomas of the mandible in an 8-year-old girl with Noonan syndrome (Noonan-like/multiple giant cell lesion syndrome)



Bilateral central giant cell granulomas of the mandible in an 8-year-old girl with Noonan syndrome (Noonan-like/multiple giant cell lesion syndrome)



Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics 99(3): 334-340



We report a case of an 8-year-old girl who presented with bilateral central giant cell granulomas of the posterior mandible. Characteristic facial features and a history of pulmonary stenosis led us to suspect a diagnosis of Noonan syndrome. A medical geneticist confirmed this. This case report will discuss the salient features of this diagnosis.

(PDF emailed within 0-6 h: $19.90)

Accession: 011803568

Download citation: RISBibTeXText

PMID: 15716842

DOI: 10.1016/j.tripleo.2004.08.021



Related references

A novel PTPN11 gene mutation bridges Noonan syndrome, multiple lentigines/LEOPARD syndrome and Noonan-like/ multiple giant cell lesion syndrome. European Journal of Human Genetics 12(12): 1069-1072, 2004

Noonan-like/multiple giant cell lesion syndrome A separate entity from Noonan syndrome?. American Journal of Human Genetics 67(4 Supplement 2): 118, October, 2000

Are Noonan syndrome and Noonan-like/multiple giant cell lesion syndrome distinct entities?. American Journal of Medical Genetics 98(3): 230-234, January 22, 2001

Noonan-like/multiple giant cell lesion syndrome. American Journal of Medical Genetics 40(2): 159-166, 1991

SOS1: a new player in the Noonan-like/multiple giant cell lesion syndrome. Clinical Genetics 75(6): 568-571, 2009

Aggressive noonan-like multiple giant cell lesion syndrome on Tc-99m MDP bone scan. Clinical Nuclear Medicine 34(12): 913-915, 2010

Phenotypic and genotypic characterisation of Noonan-like/multiple giant cell lesion syndrome. Journal of Medical Genetics 42(2): E11-E11, 2005

Noonan-like/multiple giant cell lesion syndrome: report of a case and review of the literature. Journal of Oral and Maxillofacial Surgery 64(8): 1289-1292, 2006

Noonan-like/multiple giant cell lesion syndrome in two adult patients with SOS1 gene mutations. Clinical Dysmorphology 19(3): 157-160, 2010

Case report: Noonan-like multiple central giant cell granuloma syndrome. Pediatric Dentistry 34(5): 144-147, 2013

Polyarticular pigmented villonodular synovitis associated with multiple congenital anomalies. A case of Noonan-like/multiple giant cell lesion syndrome. Clinical and Experimental Rheumatology 14(2): 207-210, 1996

Unilateral giant cell lesion of the jaw in Noonan syndrome. Jbr-Btr 97(2): 90-93, 2014

Giant cell lesion of the jaw as a presenting feature of Noonan syndrome. Bmj Case Reports 2018, 2018

Noonan syndrome associated with central giant cell granuloma. Clinical Genetics. 53(5): 411-414,, 1998

A case of neurofibromatosis-Noonan syndrome with a central giant cell granuloma. Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontics 98(3): 316-320, 2004