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Cardiac matrix remodelling in congestive heart failure: the role of matrix metalloproteinases



Cardiac matrix remodelling in congestive heart failure: the role of matrix metalloproteinases



Clinical and Investigative Medicine. Medecine Clinique et Experimentale 27(2): 93-100



Background: Congestive heart failure (CHF), the most frequent reason for hospital admission of elderly patients, is an important and rapidly increasing cause of morbidity and mortality worldwide. Its development is accompanied by left-ventricle (LV) dilatation and pump dysfunction. The extracellular space in the heart is now recognized as an essential element of myocardial structure and function, and a dynamic participant in remodelling.

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Accession: 011831780

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PMID: 15202828


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