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Comparative analysis of thymidylate synthase, thymidine phosphorylase and dihydropyrimidine dehydrogenase expression in colorectal cancer and surrounding normal tissue



Comparative analysis of thymidylate synthase, thymidine phosphorylase and dihydropyrimidine dehydrogenase expression in colorectal cancer and surrounding normal tissue



Neoplasma 52(3): 208-210



Thymidylate synthase thymidine phosphorylase and dihydropyrimidine dehydrogenase play the essential role in the activation and catabolism of the fluoropyrimidines used in cancer therapy. It's expression may influence the antitumor activity or toxicity of these drugs.

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Accession: 011878151

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PMID: 15875081


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