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Comparison of coronary artery calcification detected by electron beam computed tomography in coronary artery ectasia and in stenotic coronary artery disease



Comparison of coronary artery calcification detected by electron beam computed tomography in coronary artery ectasia and in stenotic coronary artery disease



Zhonghua Xinxueguanbing Zazhi 32(1): 13-16



Objective To compare the difference of coronary artery calcification ( CAC) detected by electron beam computed tomography ( EBCT) in atherosclerotic coronary artery ectasia and in stenotic coronary artery disease. Methods 24 patients with atherosclerotic coronary artery ectasia ( group CAE) underwent EBCT for calculating calcium score (CS). Their calcium extent was compared with 24 patients with stenotic coronary artery disease but without any evidence of ectasia (group CHD), matched for sex, age and stenotic severity with the patients in group CAE. Results (1) There were no significant differences between groups in clinical baseline data, stenotic severity and lesion arteries. (2) The natural logarithm transformation of CS (LN ( CS + 1)) was 3.41 +/- 2.44 in group CAE vs. 4. 88 +/- 2. 48 in group CHD (P 0. 05). (3) The calcium extent was related to lesion type of ectasia, and LN ( CS + 1) was significantly lower in vessels with diffuse ectasia than in those with discrete ectasia (1. 26 +/- 1. 85 vs 2. 67 +/- 1. 93, P 0. 05). (4) The LN ( CS + 1) of the arteries with ectasia alone and those with both ectasia and stenosis were significantly lower than that of the vessels with stenosis alone (P 0. 01 or 0. 05). Conclusion Coronary artery calcification is less extensive in patients with atherosclerotic coronary artery ectasia than in those with coronary artery disease without ectasia, and the calcium score is related to lesion type. Our findings suggest that plaque calcification might be associated with the pathogenesis of ectasia.

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