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Compensatory kidney growth in estrogen receptor-alpha null mice

Compensatory kidney growth in estrogen receptor-alpha null mice

American Journal of Physiology Renal Physiology 290(2): F319-F323

ISSN/ISBN: 1931-857X

Females are relatively protected in many progressive kidney diseases. Processes of kidney scarring and growth are intricately linked, and female kidneys are smaller than male kidneys. To better understand links between sex, growth, and the kidney, we examined compensatory kidney growth (CKG) after uninephrectomy (Unx) in wild-type and estrogen receptor-alpha null mice (ERKO). Mice (10 wk old) underwent Unx or sham procedure, with removal of all remaining kidney(s) 48 h later.

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Accession: 011887894

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