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Crystallization and X-ray crystallographic studies of wild-type and mutant tryptophan synthase alpha-subunits from Escherichia coli



Crystallization and X-ray crystallographic studies of wild-type and mutant tryptophan synthase alpha-subunits from Escherichia coli



Molecules and Cells 19(2): 219-222



The alpha-subunit of Escherichia coli tryptophan synthase (alpha TS), a component of the tryptophan synthase alpha(2)beta(2) complex, is a monomeric 268-residues protein (Mr = 28,600). alpha TS by itself catalyzes the cleavage of indole-3-glycerol phosphate to glyceraldehyde-3-phosphate and indole, which is converted to tryptophan in tryptophan biosynthesis.

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Accession: 011912773

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PMID: 15879705


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