+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Cumulative high doses of inhaled formoterol have less systemic effects in asthmatic children 6-11 years-old than cumulative high doses of inhaled terbutaline



Cumulative high doses of inhaled formoterol have less systemic effects in asthmatic children 6-11 years-old than cumulative high doses of inhaled terbutaline



British Journal of Clinical Pharmacology 58(4): 411-418



Objectives To evaluate high dose tolerability and relative systemic dose potency between inhaled clinically equipotent dose increments of formoterol and terbutaline in children. Methods Twenty boys and girls (6-11 years-old) with asthma and normal ECGs were studied.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 011914035

Download citation: RISBibTeXText

PMID: 15373934

DOI: 10.1111/j.1365-2125.2004.02178.x


Related references

A randomized, double-blind, double-dummy, safety crossover trial comparing cumulative doses up to 96 microg of formoterol delivered via an HFA-134a-propelled pMDI vs. same cumulative doses of formoterol DPI and placebo in asthmatic patients. Respiration; International Review of Thoracic Diseases 72(Suppl. 1): 28-34, 2005

Tolerability of inhaled high doses of formoterol and salbutamol in asthmatic patients maintained on twice daily formoterol 12 mug. European Respiratory Journal Suppl. 10(25): 103S, 1997

Tolerability of high cumulative doses of the HFA modulite beclomethasone dipropionate/formoterol combination inhaler in asthmatic patients. Pulmonary Pharmacology and Therapeutics 21(3): 551-557, 2008

Pharmacokinetics and pharmacodynamics of cumulative single doses of inhaled salbutamol enantiomers in asthmatic subjects. Pulmonary Pharmacology and Therapeutics 12(6): 353-362, 1999

Effect of inhaled indomethacin in asthmatic patients taking high doses of inhaled corticosteroids. Journal of Allergy & Clinical Immunology 105(6 Part 1): 1134-1139, 2000

Formoterol (Foradil) and medium-high doses of inhaled corticosteroids are more effective than high doses of corticosteroids in moderate-to-severe asthma. Pulmonary Pharmacology and Therapeutics 16(5): 299-306, 2003

The biochemical effects of cumulative doses of inhaled salbutamol in normal subjects. British Journal of Clinical Pharmacology 26(5): 626P, 1988

Cumulative toxic effects of repeated doses of inhaled GB vapor in dogs. Technical Report. Cwlr. U.S. Army Chemical Warfare Laboratories 2384: 1-20, 1960

Tolerability to high doses of formoterol and terbutaline via Turbuhaler for 3 days in stable asthmatic patients. European Respiratory Journal 12(3): 573-579, 1998

Cumulative dose response study comparing clinical effects of two doses of terbutaline sulphate administered via a 750 ml spacer to asthmatic patients. Allergy 39(1): 13-16, 1984

Metabolic effects of high g g m 2 systemic cumulative doses of cisplatinum. Gynecologic Oncology 32(1): 129, 1989

Cumulative dose response study comparing clinical effects of 2 doses of terbutaline sulfate administered via a 750 milliliter spacer to asthmatic patients. Allergy 39(1): 13-16, 1984

Comparison of inhaled terbutaline and inhaled terbutaline plus ipratropium bromide in acute asthmatic children. Asian Pacific Journal of Allergy and Immunology 8(1): 45-48, 1990

Comparison of the effects of prolonged treatment with low and high doses of inhaled terbutaline on beta-adrenoceptor responsiveness in patients with chronic obstructive pulmonary disease. American Review of Respiratory Disease 142(2): 338-342, 1990

Therapeutic and metabolic effects of high (greater than 1 g/m2) systemic cumulative doses of cis-platinum in patients with ovarian carcinoma. Gynecologic Oncology 37(2): 250-253, 1990