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Cytotoxic constituents of Rhododendron brachycarpum


, : Cytotoxic constituents of Rhododendron brachycarpum. Yakhak Hoeji 49(3): 244-248

From the methanol extract of Rhododendron brachycarpum four triterpenes, three phenylpropanes and a diterpene kalkaloid were isolated. Their structures were identified as glutinol (1), 3 beta-hydroxyurs-12-ene (2), beta-sitosterol (3), (E)-p-hydroxycinnamic acid hexadecylester (4), (-)-rhododendrol (5), (+)-rhododendrol (6), 3 beta-hydroxyurs-12-en-28-oic acid (7) and gray-anotoxin 1 (8) by spectroscopic methods.

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Related references

Voss, D.H., 2001: Validation of botanical names: Rhododendron brachycarpum ssp. tigerstedtii and Rhododendron maximum var. leachii. The validation of Rhododendron brachycarpum subsp. tigerstedtii and R. maximum var. leachii is presented.

Nitzelius, T.G., 1970: Rhododendron brachycarpum ssp. tigerstedtii, a new subspecies. Vegetative and flowering characteristics are described for this plant, distinguishing it from the subspecies brachycarpo which is widely distributed in commerce.

Choi J.S.; Young H.S.; Park J.C.; Choi J H.; Woo W.S., 1986: Flavonoids from the leaves of rhododendron brachycarpum. The flavonoids isolated from the leaves of Rhododendron brachycarpum were identified as quercetin, avicularin, quercitrin and hyperin.

Hong, H.O.; Lee, G.E.; Yoo, K.C.; Han, K.H., 1983: Studies on the wild Rhododendron brachycarpum in Korea. II. The environment of naturally growing R. brachycarpum at 2 localities was compared with that of garden plants. Data are tabulated on light intensity, elevation a.s.l., moisture levels, temperature, soil nutrient content and maximum water holding ca...

Westhoff, J., 2001: Rh. brachycarpum and Rh. metternichii in the Rhododendron Park, Bremen. Anatomical features differentiating the species R. brachycarpum and R. metternichii [R. degronianum] are described. Details on rhododendrons found in the Bremen Rhododendron Park and the history of nomenclature of the species are presented.

Uosukainen, M., 1992: Rhododendron brachycarpum subsp. tigerstedtii Ntz. -- A transmitter of extreme frosthardiness. Acta Horticulturae 320: 77-83

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Zhou, W.; Oh, J.; Wonhwa, L.; Kwak, S.; Li, W.; Chittiboyina, A.G.; Ferreira, D.; Hamann, M.T.; Lee, S.Ho.; Bae, J-Sup.; Na, M., 2014: The first cyclomegastigmane rhododendroside A from Rhododendron brachycarpum alleviates HMGB1-induced sepsis. Endangered plant species are a vital resource for exploring novel drug prototypes. A Korean endangered plant Rhododendron brachycarpum G. Don is a broad-leaved shrub native to northern Korea and central Japan. The high mobility group box 1 protein...

Currha, R.S.; Tsuneda, A.; Murakami, S., 1993: Conidiogenesis in Oidiodendron periconioides and ultrastructure of ericoid mycorrhizas formed with Rhododendron brachycarpum. Oidiodendron periconioides was isolated from hair roots of seedlings of Rhododendron brachycarpum growing in pots containing a commercial peat moss in Japan. The unusual process of conidiogenesis in O. periconioides involved the formation of conid...

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