Developmental acquisition of voltage-dependent conductances and sensory signaling in hair cells of the embryonic mouse inner ear
Géléoc, Gëlle.S.G.; Risner, J.R.; Holt, J.R.
Journal of Neuroscience the Official Journal of the Society for Neuroscience 24(49): 11148-11159
ISSN/ISBN: 0270-6474 PMID: 15590931 DOI: 10.1523/jneurosci.2662-04.2004
How and when sensory hair cells acquire the remarkable ability to detect and transmit mechanical information carried by sound and head movements has not been illuminated. Previously, we defined the onset of wmechanotransduction in embryonic hair cells of mouse vestibular organs to be at approximately embryonic day 16 (E16). Here we examine the functional maturation of hair cells in intact sensory epithelia excised from the inner ears of embryonic mice.