Section 12
Chapter 11,948

Developmental acquisition of voltage-dependent conductances and sensory signaling in hair cells of the embryonic mouse inner ear

Géléoc, Gëlle.S.G.; Risner, J.R.; Holt, J.R.

Journal of Neuroscience the Official Journal of the Society for Neuroscience 24(49): 11148-11159


ISSN/ISBN: 0270-6474
PMID: 15590931
DOI: 10.1523/jneurosci.2662-04.2004
Accession: 011947608

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How and when sensory hair cells acquire the remarkable ability to detect and transmit mechanical information carried by sound and head movements has not been illuminated. Previously, we defined the onset of wmechanotransduction in embryonic hair cells of mouse vestibular organs to be at approximately embryonic day 16 (E16). Here we examine the functional maturation of hair cells in intact sensory epithelia excised from the inner ears of embryonic mice.

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