EurekaMag
+ Translate
+ Most Popular
The pigeon tick (Argas reflexus): its biology, ecology, and epidemiological aspects
Prevalence of hemoglobin abnormalities in Kebili (Tunisian South)
Lipogranuloma: a preventable complication of dacryocystorhinostomy
Value of basal plasma cortisol assays in the assessment of pituitary-adrenal insufficiency
Bees from the Belgian Congo. The acraensis group of Anthophora
Placing gingival retraction cord
Total serum IgE, allergy skin testing, and the radioallergosorbent test for the diagnosis of allergy in asthmatic children
Acariens plumicoles Analgesoidea parasites des oiseaux du Maroc
Injuries of terminal phalanges of the fingers in children
Biology of flowering and nectar production in pear (Pyrus communis)
Das Reliktvorkommen der Aspisviper (Vipera aspis L.) im Schwarzwald
Hydrological modelling of drained blanket peatland
Pathologic morphology and clinical significance of the anomalous origin of the left circumflex coronary artery from the right coronary artery. General review and autopsy analysis of 30 cases
Cyto genetic analyses of lymphocyte cultures after exposure to calcium cyclamate
Axelrodia riesei, a new characoid fish from Upper Rio Meta in Colombia With remarks concerning the genus Axelrodia and description of a similar, sympatric, Hyphessobrycon-species
Favorable evolution of a case of tuberculosis of pancreas under antibiotic action
RIFM fragrance ingredient safety assessment, Valencene, CAS Registry Number 4630-07-3
Parenteral microemulsions: an overview
Temperate pasture: management for grazing and conservation
Evaluation of a new coprocessed compound based on lactose and maize starch for tablet formulation
Thermal expansion and cracking of three confined water-saturated igneous rocks to 800C
Revision of the genera of the tribe Stigmoderini (Coleoptera: Buprestidae) a discussion of phylogenetic relationships
Anal tuberculosis. Report of a case
Gastric tuberculosis in the past and present
Adaptive responses of the cardiovascular system to prolonged spaceflight conditions: assessment with Holter monitoring

Developmental changes in cell proliferation in the auditory midbrain of the bullfrog, Rana catesbeiana


Developmental changes in cell proliferation in the auditory midbrain of the bullfrog, Rana catesbeiana



Journal of Neurobiology 66(11): 1212-1224



ISSN/ISBN: 0022-3034

PMID: 16858692

DOI: 10.1002/neu.20301

We examined patterns of cell proliferation in the auditory midbrain (torus semicircularis) of the bullfrog, Rana catesbeiana, over larval and early postmetamorphic development, by visualizing incorporation of 5-bromo-2'-deoxyuridine (BrdU) in cycling cells. At all developmental stages, BrdU-labeled cells were concentrated around the optic ventricle. BrdU-labeled cells also appeared within the torus semicircularis itself, in a stage-specific manner. The mitotic index, quantified as the percent of BrdU-positive cells outside the ventricular zone per total cells available for label, varied over larval development. Mitotic index was low in hatchling, early larval, and late larval stages, and increased significantly in deaf period, metamorphic climax, and froglet stages. Cell proliferation was higher in metamorphic climax than at other stages, suggesting increased cell proliferation in preparation for the transition from an aquatic to an amphibious existence. The change in mitotic index over development did not parallel the change in the total numbers of cells available for label. BrdU incorporation was additionally quantified by dot-blot assay, showing that BrdU is available for label up to 72 h postinjection. The pattern of change in cell proliferation in the torus semicircularis differs from that in the auditory medulla (dorsal medullary nucleus and superior olivary nucleus), suggesting that cell proliferation in these distinct auditory nuclei is mediated by different underlying mechanisms.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 011947757

Download citation: RISBibTeXText

Related references

Cell proliferation in the forebrain and midbrain of the adult bullfrog, Rana catesbeiana. Brain Behavior and Evolution 71(1): 41-53, 2008

Afferents to the midbrain auditory center in the bullfrog, rana catesbeiana. Journal of Comparative Neurology 198(3): 421-433, 1981

Representation of waveform periodicity in the auditory midbrain of the bullfrog, Rana catesbeiana. Journal of the Association for Research in Otolaryngology: Jaro 1(1): 2-24, 2000

Coding of amplitude modulation in the auditory midbrain of the bullfrog (Rana catesbeiana) across metamorphosis. Journal of Comparative Physiology. A Sensory Neural and Behavioral Physiology 184(2): 219-231, 1999

Plasticity of auditory medullary-midbrain connectivity across metamorphic development in the bullfrog, Rana catesbeiana. Brain Behavior and Evolution 69(1): 1-19, 2007

Evoked auditory activity within the telencephalon of the bullfrog (Rana catesbeiana). Brain Research 182(2): 303-311, 1980

The electrical response of the auditory mechanism in the bullfrog (Rana catesbeiana). Journal of Comparative and Physiological Psychology 52(2): 157-162, 1959

Cell proliferation in the Rana catesbeiana auditory medulla over metamorphic development. Journal of Neurobiology 66(2): 115-133, 2006

Developmental changes in non-histone chromosomal proteins of bullfrog (Rana catesbeiana). Comparative Biochemistry and Physiology. B Comparative Biochemistry 72(2): 261-265, 1982

Anatomical and functional organization of the auditory region in the mesencephalon of the bullfrog Rana catesbeiana. Dissertation Abstracts 25: 4226-4227, 1965

Immunocytochemical distribution of neurochemicals in the auditory torus semicircularis of the bullfrog, Rana catesbeiana. American Zoologist 39(5): 18A, 1999

Developmental and diel profiles of plasma corticosteroids in the bullfrog, Rana catesbeiana. Comparative Biochemistry and Physiology. Part A Molecular and Integrative Physiology 135(4): 585-595, 2003

Indications of competition between the introduced North American bullfrog Rana catesbeiana and indigenous green frogs Hinweise zur Konkurrenz zwischen ein-geschlepptem Ochsenfrosch Rana catesbeiana und einheimischen Gruenfroeschen. Herpetofauna (Weinstadt). 2003- April; 25143: 29-38, 2004

Evaluation methods of feces collection for determination of protein digestibility in bullfrog Rana catesbeiana Avaliacao de metodos de coleta de fezes para determinacao da digestibilidade proteica em ra-touro Rana catesbeiana. Ciencia Rural. mai-jun; 363: 954-958, 2006

Changes in the serotonin-, somatostatin- and motilin-immunoreactive cells in the gastrointestinal tract of the bullfrog, Rana catesbeiana, at various developmental stages. Korean Journal of Biological Sciences 3(1): 97-102, 1999