EurekaMag
+ Most Popular
Cunninghamia lanceolata plantations in China
Mammalian lairs in paleo ecological studies and palynology
Studies on technological possibilities in utilization of anhydrous milk fat for production of recombined butter-like products
Should right-sided fibroelastomas be operated upon?
Large esophageal lipoma
Apoptosis in the mammalian thymus during normal histogenesis and under various in vitro and in vivo experimental conditions
Poissons characoides nouveaux ou non signales de l'Ilha do Bananal, Bresil
Desensitizing efficacy of Colgate Sensitive Maximum Strength and Fresh Mint Sensodyne dentifrices
Administration of fluid by subcutaneous infusion: revival of a forgotten method
Tundra mosquito control - an impossible dream?
Schizophrenia for primary care providers: how to contribute to the care of a vulnerable patient population
Geochemical pattern analysis; method of describing the Southeastern limestone regional aquifer system
Incidence of low birth weights in a hospital of Mexico City
Tabanidae
Graded management intensity of grassland systems for enhancing floristic diversity
Microbiology and biochemistry of cheese and fermented milk
The ember tetra: a new pygmy characid tetra from the Rio das Mortes, Brazil, Hyphessobrycon amandae sp. n. (Pisces, Characoidei)
Risk factors of contrast-induced nephropathy in patients after coronary artery intervention
Renovation of onsite domestic wastewater in a poorly drained soil
Observations of the propagation velocity and formation mechanism of burst fractures caused by gunshot
Systolic blood pressure in a population of infants in the first year of life: the Brompton study
Haematological studies in rats fed with metanil yellow
Studies on pasteurellosis. I. A new species of Pasteurella encountered in chronic fowl cholera
Dormancy breaking and germination of Acacia salicina Lindl. seeds
therapy of lupus nephritis. a two-year prospective study

Diffuse venous thromboemboli associated with IVIg therapy in the treatment of streptococcal toxic shock syndrome: case report and review


Diffuse venous thromboemboli associated with IVIg therapy in the treatment of streptococcal toxic shock syndrome: case report and review



Annals of Hematology 84(9): 601-604



ISSN/ISBN: 0939-5555

PMID: 15815906

DOI: 10.1007/s00277-005-1043-3

Streptococcal toxic shock syndrome (STSS) is a severe invasive disease with a 40-80% mortality rate. Inflammatory cytokines induced by streptococcal pyrogenic exotoxins (SPEs) produce the clinical manifestations of a flu-like syndrome, followed by high fevers and multiorgan failure. Previously published reports have described the use of intravenous immunoglobulin (IVIg) as adjunctive treatment for STSS. However, concerns have been raised about the thromboembolic complications of this therapy. We report a severe case of STSS treated with two adjunctive courses of IVIg complicated by severe bilateral pulmonary thromboemboli. To our knowledge, this is the only reported case of thromboemboli associated with IVIg for STSS. The results of this case support the cautious use of IVIg for STSS and demonstrate the need for controlled trials to determine the appropriate timing, dosage, and course of treatment.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 011960553

Download citation: RISBibTeXText

Related references

Adjunctive treatment of streptococcal toxic shock syndrome using intravenous immunoglobulin: case report and review. American Journal of Medicine 102(1): 111-113, 1997

Acute group G streptococcal myositis associated with streptococcal toxic shock syndrome: case report and review. Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 23(5): 1159-1161, 1996

Intravenous immunoglobulin as adjunctive treatment for streptococcal toxic shock syndrome associated with necrotizing fasciitis: Case report and review. Pharmacotherapy 19(9): 1094-1098, 1999

Streptococcal toxic shock-like syndrome: case report and review of the literature. Annals of Tropical Paediatrics 14(2): 145-148, 1994

Streptococcal toxic shock syndrome in a postpartum woman. Case report and review of the literature. Infection 24(2): 164-167, 1996

Streptococcal toxic shock syndrome revealed by a peritonitis. Case report and review of the literature. Swiss Surgery 7(1): 25-27, 2001

Superantigenic activity produced by group A streptococcal isolates is neutralized by plasma from IVIG-treated streptococcal toxic shock syndrome patients. Advances in Experimental Medicine and Biology 418: 563-566, 1997

Group B streptococcal toxic shock syndrome in an asplenic patient: case report and literature review. European Journal of Clinical Microbiology and Infectious Diseases: Official Publication of the European Society of Clinical Microbiology 25(3): 208-210, 2006

Group B Streptococcal Necrotizing Fasciitis and Toxic Shock-Like Syndrome: A Case Report and Review of the Literature. Scandinavian Journal of Infectious Diseases 35(11-12): 879-882, 2003

Group B streptococcal necrotizing fasciitis and toxic shock-like syndrome: a case report and review of the literature. Scandinavian Journal of Infectious Diseases 35(11-12): 878-881, 2003

IVIG for Streptococcal Toxic Shock Syndrome. Infectious Disease in Clinical Practice 9(1): 1-2, 2000

Group A Streptococcal Toxic Shock-Like Syndrome in a Male Presenting as Primary Peritonitis: A Case Report and a Review in Japan. Case Reports in Gastrointestinal Medicine 2019: 4984679, 2019

Severe group A streptococcal toxic shock syndrome presenting as primary peritonitis: a case report and brief review of the literature. International Journal of Infectious Diseases: Ijid: Official Publication of the International Society for Infectious Diseases 14 Suppl. 3: E208-E212, 2010

Group A streptococcal toxic shock syndrome associated with pelvic peritonitis following diagnostic hysteroscopy in a healthy woman: a case report and review. Gynecological Surgery 6(2): 161-164, 2009

Diagnosis and treatment of streptococcal toxic shock syndrome in the pediatric intensive care unit: a case report. Revista Brasileira de Terapia Intensiva 31(4): 586-591, 2019