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Do age and extended culture affect the architecture of the zona pellucida of human oocytes and embryos?

Kilani, S.S.; Cooke, S.; Kan, A.K.; Chapman, M.G.

Zygote 14(1): 39-44

2006


ISSN/ISBN: 0967-1994
PMID: 16700974
DOI: 10.1017/s0967199406003625
Accession: 011972138

Advanced female age and extended in vitro culture have both been implicated in zona pellucida (ZP) hardening and thickening. This study aimed to determine the influence of (i) the woman's age and (ii) prolonged in vitro culture of embryos on ZP thickness and density using non-invasive polarized light (LC-PolScope) microscopy.

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