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Early pathophysiological features in canine renal papillary necrosis induced by nefiracetam



Early pathophysiological features in canine renal papillary necrosis induced by nefiracetam



Toxicologic Pathology 33(5): 561-569



To ascertain the early pathophysiological features in canine renal papillary necrosis (RPN) caused by the neurotransmission enhancer nefiracetam, male beagle dogs were orally administered nefiracetam at 300 mg/kg/day for 4 to 7 weeks in comparison with ibuprofen, a non-steroidal antiinflammatory drug (NSAID), at 50 mg/kg/day for 5 weeks.

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Accession: 011985481

Download citation: RISBibTeXText

PMID: 16105799

DOI: 10.1080/01926230500222593


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