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Evaluation of genotoxicity of 3-amino-, 3-acetylamino- and 3-nitrobenzanthrone using the Ames/Salmonella assay and the Comet assay

Evaluation of genotoxicity of 3-amino-, 3-acetylamino- and 3-nitrobenzanthrone using the Ames/Salmonella assay and the Comet assay

Journal of Health Science 51(5): 569-575

3-Nitrobenzanthrone (3-NBA) is an extremely potent direct-acting bacterial mutagen that has been detected in diesel exhaust particles, airborne particles and so forth. Recently, 3-aminobenzanthrone (3-ABA) and 3-acetylaminobenzanthrone (3-AABA) were identified as metabolites of 3-NBA in mammalian cells.

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Accession: 012058015

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DOI: 10.1248/jhs.51.569

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