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Genome amplification of single sperm using multiple displacement amplification

Genome amplification of single sperm using multiple displacement amplification

Nucleic Acids Research 33(10): E91-E91

Sperm typing is an effective way to study recombination rate on a fine scale in regions of interest. There are two strategies for the amplification of single meiotic recombinants: repulsion-phase allele-specific PCR and whole genome amplification (WGA). The former can selectively amplify single recombinant molecules from a batch of sperm but is not scalable for high-throughput operation.

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Accession: 012122399

Download citation: RISBibTeXText

PMID: 15942023

DOI: 10.1093/nar/gni089

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