+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

In-line filters in central venous catheters in a neonatal intensive care unit



In-line filters in central venous catheters in a neonatal intensive care unit



Journal of Perinatal Medicine 34(1): 71-74



Nosocomial sepsis remains an important cause of morbidity in neonatal intensive care units. Central venous catheters (CVCs) and parenteral nutrition (TPN) are major risk factors. In-line filters in the intravenous (IV) administration sets prevent the infusion of particles, which may reduce infectious complications. We randomized infants to in-line filter (for clear fluids and lipid emulsions) or no filter placement. Sepsis, nursing time and costs were assessed. IV sets without filters were changed every 24 h, IV-sets with filters every 96 h. Of 442 infants with a CVC, 228 were randomized to filter placement, 214 to no filter. No differences were found in clinical characteristics, CVC-use, and catheter days. Nosocomial sepsis occurred in 37 (16.2%) infants with filters, in 35 (16.3%) in the group without filter (NS). Nursing time to change the IV-administration sets was 4 min shorter in the filter-group (P<0.05). Costs of materials used were comparable. In conclusion, the incidence of sepsis when using filters was not reduced but the nursing time for changing the intravenous sets was reduced without a difference in costs.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 012195489

Download citation: RISBibTeXText

PMID: 16489888

DOI: 10.1515/jpm.2006.009


Related references

Central venous line sepsis in the intensive care unit. A study comparing antibiotic coated catheters with plain catheters. Anaesthesia 51(11): 1018-1020, 1996

Thrombus detection on central venous catheters in the neonatal intensive care unit. Angiology 45(6): 477-480, 1994

Vancomycin usage in central venous catheters in a neonatal intensive care unit. Pediatric Infectious Disease Journal 23(3): 201-206, 2004

Central line-associated bloodstream infection in hospitalized children with peripherally inserted central venous catheters: extending risk analyses outside the intensive care unit. Clinical Infectious Diseases 52(9): 1108-1115, 2011

Effectiveness of Minocycline and Rifampin vs Chlorhexidine and Silver Sulfadiazine-Impregnated Central Venous Catheters in Preventing Central Line-Associated Bloodstream Infection in a High-Volume Academic Intensive Care Unit: A Before and after Trial. Journal of the American College of Surgeons 221(3): 739-747, 2015

Comparison of triple-lumen central venous catheters impregnated with silver nanoparticles (AgTive®) vs conventional catheters in intensive care unit patients. Journal of Hospital Infection 82(2): 101-107, 2012

Peripherally inserted central catheters are equivalent to centrally inserted catheters in intensive care unit patients for central venous pressure monitoring. Journal of Clinical Monitoring and Computing 26(2): 85-90, 2012

Complication rates among peripherally inserted central venous catheters and centrally inserted central catheters in the medical intensive care unit. Journal of Critical Care 31(1): 238-242, 2016

Unnecessary use of central venous catheters: the need to look outside the intensive care unit. Infection Control and Hospital Epidemiology 25(3): 266-268, 2004

The incidence of complications of central venous catheters at an intensive care unit. Annals of Thoracic Medicine 2(2): 61-63, 2007

Use of central venous catheters is common in neonatal intensive care units. Journal of Perinatology 15(6): 519, 1995

Effectiveness and complications of percutaneous central venous catheters in neonatal intensive care. Klinische Padiatrie 206(1): 18-21, 1994

Percutaneous central venous catheters in neonatal intensive care. Personal experience. Le Journal Medical Libanais. Lebanese Medical Journal 41(4): 213-217, 1993

Comparison of Oligon catheters and chlorhexidine-impregnated sponges with standard multilumen central venous catheters for prevention of associated colonization and infections in intensive care unit patients: a multicenter, randomized, controlled study. Critical Care Medicine 40(2): 420-429, 2012

Central venous catheters in the pediatric intensive care unit: access versus infection. Pediatric Critical Care Medicine 4(4): 491-492, 2003