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Individual differences in dopamine efflux in nucleus accumbens shell and core during instrumental learning

Individual differences in dopamine efflux in nucleus accumbens shell and core during instrumental learning

Learning & Memory 13(2): 168-177

Combined activation of dopamine D1- and NMDA-glutamate receptors in the nucleus accumbens has been strongly implicated in instrumental learning, the process in which an individual learns that a specific action has a wanted outcome. To assess dopaminergic activity, we presented rats with two sessions (30 trials each) of a one-lever appetitive instrumental task and simultaneously measured dopamine efflux in the shell and core accumbens subareas using in vivo microdialysis.

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Accession: 012202118

Download citation: RISBibTeXText

PMID: 16585792

DOI: 10.1101/lm.1806

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