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Interaction of severe acute respiratory syndrome-associated coronavirus with dendritic cells



Interaction of severe acute respiratory syndrome-associated coronavirus with dendritic cells



Journal of General Virology 87(Pt 7): 1953-1960



Severe acute respiratory syndrome (SARS) of humans is caused by a novel coronavirus of zoonotic origin termed SARS-associated coronavirus (SARS-CoV). The virus induces severe injury of lung tissue, as well as lymphopenia. and destruction of the architecture of lymphatic tissue by as-yet-unknown mechanisms. In this study, the interaction of SAIRS-CoV with dendritic cells (DCs), the key regulators of immune responses, was analysed.

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Accession: 012224681

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PMID: 16760397


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