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Major histocompatibility complex class I-intercellular adhesion molecule-1 association on the surface of target cells: implications for antigen presentation to cytotoxic T lymphocytes

Lebedeva, T.; Anikeeva, N.; Kalams, S.A.; Walker, B.D.; Gaidarov, I.; Keen, J.H.; Sykulev, Y.

Immunology 113(4): 460-471

2004


ISSN/ISBN: 0019-2805
PMID: 15554924
DOI: 10.1111/j.1365-2567.2004.01985.x
Accession: 012282923

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Polarization and segregation of the T-cell receptor (TCR) and integrins upon productive cytotoxic T-lymphocyte (CTL) target cell encounters are well documented. Much less is known about the redistribution of major histocompatibility complex class I (MHC-I) and intercellular adhesion molecule-1 (ICAM-1) proteins on target cells interacting with CTLs.

Major histocompatibility complex class I-intercellular adhesion molecule-1 association on the surface of target cells: implications for antigen presentation to cytotoxic T lymphocytes

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