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Mechanisms and significance of eryptosis



Mechanisms and significance of eryptosis



Antioxidants & Redox Signaling 8(7-8): 1183-1192



Suicidal death of erythrocytes (eryptosis) is characterized by cell shrinkage, membrane blebbing, activation of proteases, and phosphatidylserine exposure at the outer membrane leaflet. Exposed phosphatidylserine is recognized by macrophages that engulf and degrade the affected cells. Eryptosis is triggered by erythrocyte injury after several stressors, including oxidative stress.

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Accession: 012293769

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PMID: 16910766

DOI: 10.1089/ars.2006.8.1183


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