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Neovascularization of poly(ether ester) block-copolymer scaffolds in vivo: long-term investigations using intravital fluorescent microscopy



Neovascularization of poly(ether ester) block-copolymer scaffolds in vivo: long-term investigations using intravital fluorescent microscopy



Journal of Biomedical Materials Research. Part A 68(1): 10-18



Poly(ether ester) block-copolymer scaffolds of different pore size were implanted into the dorsal skinfold chamber of balb/c mice. Using intravital fluorescent microscopy, the temporal course of neovascularization into these scaffolds was quantitatively analyzed. Three scaffold groups (diameter, 5 mm; 220-260 thickness, mum; n=30) were implanted. Different pore sizes were evaluated: small (20-75 mum), medium (75-212 mum) and large pores (250-300 mum).

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Accession: 012345586

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PMID: 14661244

DOI: 10.1002/jbm.a.20016


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