Section 13
Chapter 12,383

Origins and evolution of the recA/RAD51 gene family: evidence for ancient gene duplication and endosymbiotic gene transfer

Lin, Z.; Kong, H.; Nei, M.; Ma, H.

Proceedings of the National Academy of Sciences of the United States of America 103(27): 10328-10333


ISSN/ISBN: 0027-8424
PMID: 16798872
DOI: 10.1073/pnas.0604232103
Accession: 012382962

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The bacterial recA gene and its eukaryotic homolog RAD51 are important for DNA repair, homologous recombination, and genome stability. Members of the recA/RAD51 family have functions that have differentiated during evolution. However, the evolutionary history and relationships of these members remains unclear. Homolog searches in prokaryotes and eukaryotes indicated that most eubacteria contain only one recA.

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