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Peptide domain involved in the interaction between membrane protein and nucleocapsid protein of SARS-associated coronavirus



Peptide domain involved in the interaction between membrane protein and nucleocapsid protein of SARS-associated coronavirus



Journal of Biochemistry and Molecular Biology 38(4): 381-385



Severe acute respiratory syndrome (SARS) is an emerging infectious disease associated with a novel coronavirus (CoV) that was identified and molecularly characterized in 2003. Previous studies on various coronaviruses indicate that protein-protein interactions amongst various coronavirus proteins are critical for viral assembly and morphogenesis. It is necessary to elucidate the molecular mechanism of SARS-CoV replication and rationalize the anti-SARS therapeutic intervention.

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Accession: 012401833

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PMID: 16053703


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