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Pilot study of rapid infusion of 2 L of 4 degrees C normal saline for induction of mild hypothermia in hospitalized, comatose survivors of out-of-hospital cardiac arrest



Pilot study of rapid infusion of 2 L of 4 degrees C normal saline for induction of mild hypothermia in hospitalized, comatose survivors of out-of-hospital cardiac arrest



Circulation 112(5): 715-719



Background - Recent clinical studies have demonstrated that mild hypothermia ( 32 degrees C to 34 degrees C) induced by surface cooling improves neurological outcome after resuscitation from out-of-hospital cardiac arrest. Results from animal models suggest that the effectiveness of mild hypothermia could be improved if initiated as soon as possible after return of spontaneous circulation.

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Accession: 012420212

Download citation: RISBibTeXText

PMID: 16043638

DOI: 10.1161/CIRCULATIONAHA.105.544528



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