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Preliminary study on the recombinant live vaccine against FMDV type O delivered by attenuated Salmonella choleraesuis in rabbits



Preliminary study on the recombinant live vaccine against FMDV type O delivered by attenuated Salmonella choleraesuis in rabbits



Fudan Xuebao Zirankexueban 44(4): 484-489



Recombinant strains of Salmonella choleraesuis C500 which containing eukaryotic expression plasmid pBO1 was constructed. These plasmids contained the immunodominant epitope of foot-and-mouth disease virus. Evaluation of specific immune response was performed in rabbits by oral immunization with the live recombinant pBO1/S. cho. Results showed that T cell response and specific antibodies were elicited.

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Accession: 012442133

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