+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Preparation and characterization of oridonin-loaded poly ( caprolactone)-poly ( ethylene oxide)-poly (caprolactone) copolymer nanoparticles



Preparation and characterization of oridonin-loaded poly ( caprolactone)-poly ( ethylene oxide)-poly (caprolactone) copolymer nanoparticles



Chinese Journal of Natural Medicines 3(5): 291-293



AIM: To prepare and characterize oridonin-loaded nanoparticles. METHOD: The PCL-PEO-PCL copolymers were synthesized by ring opening polymerization of caprolactone initiated by the hydroxyl groups of poly (ethylene glycol) (PEG) with stannous octoate as catalyzer. In optional solvents these copolymers could form micelles-like nanoparticles(Nps). RESULT: From SEM the drug-loaded Nps exhibited a regular spherical shape.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 012443271

Download citation: RISBibTeXText


Related references

Oridonin-loaded poly(-caprolactone)poly(ethylene oxide)poly(-caprolactone) copolymer nanoparticles: Preparation, characterization, and antitumor activity on mice with transplanted hepatoma. Journal of Drug Targeting 16(6): 479-485, 2008

Oridonin-loaded poly(epsilon-caprolactone)-poly(ethylene oxide)-poly(epsilon-caprolactone) copolymer nanoparticles: preparation, characterization, and antitumor activity on mice with transplanted hepatoma. Journal of Drug Targeting 16(6): 479-485, 2008

Rapamycin-loaded poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) nanoparticles: preparation, characterization and potential application in corneal transplantation. Journal of Pharmacy and Pharmacology 66(4): 557-563, 2014

Preparation and drug release behaviors of nimodipine-loaded poly(caprolactone)-poly(ethylene oxide)-polylactide amphiphilic copolymer nanoparticles. Biomaterials 24(13): 2395-2404, 2003

Preparation and in vitro characterization of retinoic acid-loaded poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) micelles. Research in Pharmaceutical Sciences 12(6): 465-478, 2017

Preparation and characterization of self-assembled nanoparticles formed by poly(ethylene oxide)-block-poly(epsilon-caprolactone) copolymers with long poly(epsilon-caprolactone) blocks in aqueous solutions. Langmuir 23(6): 3395-3400, 2007

Preparation and Characterization of Poly(vinyl alcohol)/Poly( -caprolactone)-Poly(ethylene glycol)-Poly( -caprolactone)/Nano-Hydroxyapatite Composite Membranes for Tissue Engineering. Journal of Nanoscience and Nanotechnology 11(3): 2354-2360, 2011

Preparation of curcumin loaded poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) nanofibers and their in vitro antitumor activity against Glioma 9L cells. Nanoscale 3(9): 3825-3832, 2011

Preparation of Tacrolimus loaded micelles based on poly(ɛ-caprolactone)-poly(ethylene glycol)-poly(ɛ-caprolactone). International Journal of Pharmaceutics 407(1-2): 184-189, 2011

Rapamycin-loaded poly -caprolactone-polyethylene glycol-poly -caprolactone nanoparticles preparation, characterization and potential application in corneal transplantation. 2013

Preparation, characterization and anticancer activity of norcantharidin-loaded poly(ethylene glycol)-poly(caprolactone) amphiphilic block copolymer micelles. Die Pharmazie 67(9): 781-788, 2012

Poly(epsilon-caprolactone)/poly(ethylene glycol)/poly(epsilon-caprolactone) nanoparticles: preparation, characterization, and application in doxorubicin delivery. Journal of Physical Chemistry. B 113(39): 12928-12933, 2009

Doxorubicin delivery via magnetic nanomicelles comprising from reduction-responsive poly(ethylene glycol)‑b‑poly(ε‑caprolactone) (PEG-SS-PCL) and loaded with superparamagnetic iron oxide (SPIO) nanoparticles: Preparation, characterization and simulation. Materials Science and Engineering. C Materials for Biological Applications 92: 631-643, 2018

Self-assembled honokiol-loaded micelles based on poly(epsilon-caprolactone)-poly(ethylene glycol)-poly(epsilon-caprolactone) copolymer. International Journal of Pharmaceutics 369(1-2): 170-175, 2009

Poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (Pluronic)/poly(epsilon-caprolactone) (PCL) amphiphilic block copolymeric nanospheres. I. Preparation and characterization. Journal of Controlled Release 62(3): 381-392, 1999