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Quantitative evaluation of tissue invasion by wild type, hyphal and SAP mutants of Candida albicans, and non-albicans Candida species in reconstituted human oral epithelium


Quantitative evaluation of tissue invasion by wild type, hyphal and SAP mutants of Candida albicans, and non-albicans Candida species in reconstituted human oral epithelium



Journal of Oral Pathology and Medicine: Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 35(8): 484-491



ISSN/ISBN: 0904-2512

PMID: 16918600

DOI: 10.1111/j.1600-0714.2006.00435.x

BACKGROUND: Oral candidosis is a common problem in compromised patients. Although several non-albicansCandida species have emerged as pathogens the majority of candidal infections are caused by Candida albicans. Morphogenesis from the blastospore to filamentous phase, and production of secretory aspartyl proteinases (SAP) are 2 major virulence attributes of these opportunistic yeast.

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Accession: 012475268

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