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Relation of C-reactive protein and one-year survival after acute myocardial infarction with versus without statin therapy

Relation of C-reactive protein and one-year survival after acute myocardial infarction with versus without statin therapy

American Journal of Cardiology 96(5): 617-621

We evaluated the interaction between inflammation and survival benefit from statin therapy in patients who had acute myocardial infarction. Although 1-year mortality did not differ between patients who used statin therapy and those who did not, among patients who had C-reactive protein (CRP) concentrations in the lower 2 tertiles (<2.9 mg/L), 1-year mortality was higher in patients who used statin therapy than in those who did not within the highest CRP-defined tertile (> or =2.9 mg/L). Statin therapy significantly decreased the hazard ratio for 1-year mortality in patients who had high CRP levels to approximately the hazard present for patients who had low CRP levels and did not receive statin therapy.

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Accession: 012500555

Download citation: RISBibTeXText

PMID: 16125481

DOI: 10.1016/j.amjcard.2005.04.030

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