SENV infection in HIV-positive patients: prevalence, subtype characterization, and impact on HIV disease progression
Quiros-Roldan, E.; Torti, C.; Imberti, L.; Casari, S.; Soriano, V.; Moretti, F.; Pirovano, S.; Carosi, G.
Aids Research and Human Retroviruses 19(12): 1079-1082
ISSN/ISBN: 0889-2229 PMID: 14709243 DOI: 10.1089/088922203771881167
Among 165 HIV-infected patients, prevalence of SEN virus (SENV) infection was 51.5%, with subtype A predominance and unique SENV variant (67%), but also SENV superinfections with multiple variants were frequent. High prevalence, superinfection and broad SENV subtype diversification have been demonstrated, all linked to intravenous drug use (IVDU) as a risk factor for HIV acquisition. At multivariate analysis, SENV infection did not appear to have any negative impact on survival, while a possible protective effect needs further investigation.