+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Severe acute respiratory syndrome coronavirus infection of human ciliated airway epithelia: role of ciliated cells in viral spread in the conducting airways of the lungs



Severe acute respiratory syndrome coronavirus infection of human ciliated airway epithelia: role of ciliated cells in viral spread in the conducting airways of the lungs



Journal of Virology 79(24): 15511-15524



Severe acute respiratory syndrome coronavirus (SARS-CoV) emerged in 2002 as an important cause of severe lower respiratory tract infection in humans, and in vitro models of the lung are needed to elucidate cellular targets and the consequences of viral infection.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 012550740

Download citation: RISBibTeXText

PMID: 16306622

DOI: 10.1128/jvi.79.24.15511-15524.2005


Related references

ACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia. Journal of Virology 79(23): 14614-14621, 2005

Human immunodeficiency viral vector pseudotyped with the spike envelope of severe acute respiratory syndrome coronavirus transduces human airway epithelial cells and dendritic cells. Human Gene Therapy 18(5): 413-422, 2007

Respiratory syncytial virus infection of human airway epithelial cells is polarized, specific to ciliated cells, and without obvious cytopathology. Journal of Virology 76(11): 5654-5666, 2002

Mouse strain modulates the role of the ciliated cell in acute tracheobronchial airway injury-distal airways. American Journal of Pathology 160(1): 315-327, 2002

Autoantibodies against human epithelial cells and endothelial cells after severe acute respiratory syndrome (SARS)-associated coronavirus infection. Journal of Medical Virology 77(1): 1-7, 2005

Vitamin A and ciliated cells. I. Respiratory epithelia. Zeitschrift für Ernahrungswissenschaft 25(2): 114-122, 1986

Dynamic innate immune responses of human bronchial epithelial cells to severe acute respiratory syndrome-associated coronavirus infection. Plos one 5(1): E8729, 2010

Voltage activated potassium channels in isolated ciliated cells from airway epithelia. Biophysical Journal 59(2 Part 2): 266A, 1991

Comparative host gene transcription by microarray analysis early after infection of the Huh7 cell line by severe acute respiratory syndrome coronavirus and human coronavirus 229E. Journal of Virology 79(10): 6180-6193, 2005

The effects of coronavirus on human nasal ciliated respiratory epithelium. European Respiratory Journal 18(6): 965-970, 2001

The effects of coronavirus on human nasal ciliated respiratory epithelium. European Respiratory Journal 18(6): 965-970, 2001

Lack of high affinity fiber receptor activity explains the resistance of ciliated airway epithelia to adenovirus infection. Journal of Clinical Investigation 100(5): 1144-1149, 1997

Adenoviral vectors modified for increased CFTR expression and persistence in human ciliated airway epithelia. American Journal of Human Genetics 65(4): A503, 1999

Mechanisms of zoonotic severe acute respiratory syndrome coronavirus host range expansion in human airway epithelium. Journal of Virology 82(5): 2274-2285, 2007

Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease. Journal of Virology 85(24): 13363-13372, 2011