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Solvent effect on cDNA-expressed human sulfotransferase (SULT) activities in vitro


Solvent effect on cDNA-expressed human sulfotransferase (SULT) activities in vitro



Drug Metabolism and Disposition: the Biological Fate of Chemicals 31(11): 1300-1305



ISSN/ISBN: 0090-9556

PMID: 14570759

DOI: 10.1124/dmd.31.11.1300

Sulfation is an important reaction in the biotransformation of steroid hormones, neurotransmitters, drugs, and other xenobiotics, yet little is known about the effects of organic solvents on sulfotransferase (SULT) activities in vitro. Initial experiments found that surprisingly low levels of solvent had dramatic effects on sulfotransferase activity.

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Accession: 012568921

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