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Chapter 12,589

Structural basis of interdomain communication in the Hsc70 chaperone

Jiang, J.; Prasad, K.; Lafer, E.M.; Sousa, R.

Molecular Cell 20(4): 513-524

2005


ISSN/ISBN: 1097-2765
PMID: 16307916
DOI: 10.1016/j.molcel.2005.09.028
Accession: 012588383

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Hsp70 family proteins are highly conserved chaperones involved in protein folding, degradation, targeting and translocation, and protein complex remodeling. They are comprised of an N-terminal nucleotide binding domain (NBD) and a C-terminal protein substrate binding domain (SBD).

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