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The possible mechanism of lung injury induced by severe acute respiratory syndrome coronavirus spike glycoprotein



The possible mechanism of lung injury induced by severe acute respiratory syndrome coronavirus spike glycoprotein



Zhonghua Jie He He Hu Xi Za Zhi 29(9): 587-590



Objective To investigate the role of severe acute respiratory syndrome coronavirus (SARS-CoV) in the induction of acute lung injury by promoting the synthesis of chemokine/cytokines in human endothelial cells. Methods Twenty-three SARS patients were enrolled in this study, comprising 15 male and 8 female, aged 27 - 55 years, mean (36 +/- 6) years. They were treated at Guangzhou Institute of Respiratory Disease from February to May in 2003.

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Accession: 012671446

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PMID: 17129463


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