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Thromboembolic and bleeding complications following St. Jude Medical valve replacement: results of the German Experience With Low-Intensity Anticoagulation Study



Thromboembolic and bleeding complications following St. Jude Medical valve replacement: results of the German Experience With Low-Intensity Anticoagulation Study



Chest 127(1): 53-59



Study objectives: Due to their inherent thrombogenicity, mechanical cardiac valves necessitate lifelong oral anticoagulation. Less intensive oral anticoagulation than recommended earlier might result in a lower incidence of bleeding complications without increasing the embolic hazard significantly. Design: Comparison of three different intensities of oral anticoagulation in a prospective, randomized multicenter design.

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Accession: 012693247

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PMID: 15653962

DOI: 10.1378/chest.127.1.53


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