+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Usefulness of jejunal biopsy in the study of intestinal malabsorption in the elderly

Usefulness of jejunal biopsy in the study of intestinal malabsorption in the elderly

Revista Espanola de Enfermedades Digestivas 96(4): 259-264

Background: small bowel structure and function are not different between elderly people and young people. Thus, in principle it is advisable to perform diagnostic investigation of elderly patients as well as younger patients when they present with symptoms suggestive of intestinal malabsorption. A key test for the etiologic diagnosis of intestinal malabsorption, jejunal biopsy, has not been specifically examined to assess its usefulness and risk of complications in this advanced age patients. Aim: to establish the usefulness of jejunal biopsy with the Watson's capsule in the elderly patients with suspected intestinal malabsorption. Patients: patients older than 65 years referred to our Unit for performance of a jejunal biopsy from 1996 to 2001 for suspicion of intestinal malabsorption. Results: forty-seven patients were included. Appropriate biopsy sample was obtained in 45 cases, although in 3 patients a second try was required. Histologic findings: partial villous atrophy in 10 cases (22.2%), complete villous atrophy in 5 cases (11.1%), intraepithelial lymphocytosis in 5 cases (11.1%), and single cases of intestinal lymphangiectasia, amyloidosis, unspecific jejunitis, and Whipple's disease. Histology was normal in 19 cases (42%). Definitive diagnosis was celiac disease in 14 patients, bacterial over-growth in 3, jejunitis in 3, Whipple's disease in 1, lymphangiectasia in 1, atrophic gastritis in 3, amyloidosis in 1, and ischemic colitis in 1. Jejunal biopsy achieved an etiologic diagnosis in 20 patients. There were no cases of perforations or bleeding. Conclusion: jejunal biopsy is a useful and safe test for the etiologic diagnosis of intestinal malabsorption in elderly patients.

Please choose payment method:

(PDF emailed within 1 workday: $29.90)

Accession: 012730343

Download citation: RISBibTeXText

PMID: 15117239

Related references

Malabsorption syndrome associated with intestinal diverticulosis. Report of a case with jejunal biopsy. Gastroenterology 42: 63-68, 1962

Usefulness Of Peroral Intestinal Biopsy In The Diagnosis Of Two Unusual Causes Of Malabsorption. Journal of the Medical Association of Georgia 53: 263-266, 1964

A study of fat malabsorption and jejunal muscosal biopsy in diabetic neuropathy: a preliminary report. Journal of the Association of Physicians of India 21(9): 777-785, 1973

Push enteroscopy and enteroscopic jejunal biopsy Is it better than gastroscopy and standard duodenal biopsy in patients with malabsorption?. Gastroenterology 116(4 PART 2): A887, April, 1999

The diagnostic value of jejunal biopsy in the malabsorption syndrome. Folia Medica Neerlandica 9(1): 33-34, 1966

Jejunal biopsy in the diagnosis of malabsorption syndromes. Diseases of the Colon and Rectum 8(6): 425-430, 1965

Ultrastructure of the jejunal biopsy in the malabsorption syndrome. Revista Medica de Chile 89: 951-953, 1961

Jejunal biopsy findings in the course of secondary malabsorption. Acta Gastro Enterol Belgica 26(11): 711-717, 1963

Malabsorptions. Information provided by jejunal biopsy in malabsorption. Lille Medical 16(6): 869-872, 1971

Endoscopic jejunal biopsy in child chronic malabsorption. La Pediatria Medica E Chirurgica 3(5): 407-409, 1981

Glucose-galactose malabsorption. A study with biopsy of the small intestinal mucosa. Acta Paediatrica Scandinavica 57(4): 273-280, 1968

Enzyme electrophoresis of jejunal biopsy material in the malabsorption syndrome. Sbornik Lekarsky 68(10): 296-302, 1966

Jejunal biopsy in malabsorption syndromes and chronic diarrhea in adults. Journal de Medecine de Lyon 49(146): 1211-1223, 1968

Data Of Jejunal Biopsy In Secondary Malabsorption. Anatomofunctional Comparison. Acta Gastro-Enterologica Belgica 26: 711-717, 1963

Biopsy of the intestinal mucosa in children. Initial results of a study of the malabsorption syndromes. La Presse Medicale 71: 1267-1270, 1963