Section 13
Chapter 12,746

Voxel-wise analysis of diffusion weighted imaging reveals disruption of the olfactory tract in Parkinson's disease

Scherfler, C.; Schocke, M.F.; Seppi, K.; Esterhammer, R.; Brenneis, C.; Jaschke, W.; Wenning, G.K.; Poewe, W.

Brain a Journal of Neurology 129(Pt 2): 538-542


ISSN/ISBN: 0006-8950
PMID: 16272163
DOI: 10.1093/brain/awh674
Accession: 012745291

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Diffusion weighted imaging (DWI) and the trace of diffusion tensor a marker of water molecule diffusivity, provide information on structural integrity of nervous tissues. To investigate structural lesions within the brain's neuronal architecture in early stages of Parkinson's disease, 12 patients with disease duration of 3.5 +/- 1.5 years were studied with DWI. Data were compared with 12 age-matched healthy control subjects.

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