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Whole genome amplification of buccal cell DNA: genotyping concordance before and after multiple displacement amplification



Whole genome amplification of buccal cell DNA: genotyping concordance before and after multiple displacement amplification



Clinical Chemistry and Laboratory Medicine 43(2): 157-162



While buccal cells provide an easily accessible source of genomic DNA, the amount extracted may be insufficient for many studies. Whole genome amplification (WGA) using multiple displacement amplification (MDA) may optimize buccal cell genomic DNA yield. We compared the usefulness, in epidemiological surveys, of DNA derived from buccal cells collected by alcohol mouthwash and amplified by WGA protocol and standard protocols.

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Accession: 012749626

Download citation: RISBibTeXText

PMID: 15843209

DOI: 10.1515/cclm.2005.026


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